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Molecular Devices

Comparison of Microplate Readers with Fluorescence Detection


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 SpectraMax M Series Multi-Mode Microplate ReadersGemini EM Microplate ReaderGemini XPS Microplate ReaderFLIPR Tetra High-Throughput Cellular Screening SystemFlexStation 3 Multi-Mode Microplate Reader
Fluorescence  x  x  x  x  x
Absorbance  x        x
Luminescence x+  x  x x  x
Time-resolved fluorescence (TRF) x+ x* x*    x
HTRF Certified x+        x
Fluorescence Polarization x+        x
Wavelength range FL 250 - 850, Abs 200 - 1000 FL 250 - 850 ex, Abs 360-850 em FL 250 - 850 ex, 250 - 850 em LEDs available in 360-626 nm range, Emission filters available in 400-706 nm range FL 250 - 850 ex, 250-850 em; Abs 200-1000
Bandwidth 9/9 or 9/15+ 9/9 9/9 Variable 9/15
Tunable wavelength selection/ monochromator  x  x  x    x
Endpoint  x  x  x    x
Kinetic  x  x  x  x  x
Spectral scanning  x  x  x    x
Well scanning  x  x  x    x
Reading speed (sec) 15-17+ 15 15 1 17
Microplate formats 6-384 6-384 6-384 96, 384, 1536 6-384**
Integrated multi-channel pipettor         x***
Temperature control  x  x  x  x  x
Top reading  x  x  x  x  x
Bottom reading x+  x      x
Cuvette port  x        x
Validation tools  x  x  x    x
Robotics / automation  x  x  x  x  x

All above trademarks are property of Molecular Devices, LLC.

* Secondary modes
**  96- and 384-well with pipetting
*** 8- and 16-channel pipettor
+ Varies by model

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