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Termékek
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Automatizált és klasszikus mikroszkópia
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Automatizált mikroszkópia
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FLIPR
- FLIPR Tetra High-Throughput Cellular Screening System
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FLIPR Tetra High-Throughput Cellular Screening System |
Industry-renowned, flexible, and reliable real-time kinetic cellular assay screening system for identifying early leads against GPCR and ion channel receptors
Quickly transform your creative concepts into real-time kinetic cellular assays for identifying early leads against GPCRs and ion channel targets. Our FLIPR Tetra® High-Throughput Cellular Screening System is fast, reliable, and remarkably easy to configure. The system is optimized for use with both fluorescence and luminescence, and adapts readily to your assay format with user-changeable 96-, 384-, and 1536-well heads.
Quickly transform your creative concepts into real-time kinetic cellular assays for identifying early leads against GPCRs and ion channel targets. Our FLIPR Tetra® High-Throughput Cellular Screening System is fast, reliable, and remarkably easy to configure. The system is optimized for use with both fluorescence and luminescence, and adapts readily to your assay format with user-changeable 96-, 384-, and 1536-well heads.
ÁRAJÁNLATOT, INFORMÁCIÓT KÉREK!
Transform your ideas into fast, effective, cellular screening assays
- Configure and switch between fluorescence or luminescence read modes for assay flexibility
- Multiple read modes support both single wavelength and ratiometric assays
- Choice of fluorescent or dual-mode cameras (FL and LUM) for increased assay flexibility
- User-changeable 96-, 384-, and 1536-pipettor heads easily change assay formats depending on your throughput needs
- Configurable pipettor height and dispense speeds ensure proper mixing without disturbing cell monolayers or non-adherent cells
- User-configurable optics supports rapid optic changes in a multi-user, multi-assay environment
- Drag-and-drop software interface easily builds multiple step protocols for easy protocol definition
- User-defined protocols can include up to four wash solvents to automate cleaning of cell handling system
- Configurable data export in either time-sequence or well-based format of single or multiple data files enables analysis by Microsoft Excel, Spotfire, or other analysis program
Take Advantage of These Great Features
- Fluorescence camera enables use of homogeneous FLIPR calcium and membrane potential kits
- Contact based elastomeric liquid transfer for 1536 pipettor provides accurate pipetting of compounds and cells
- Simultaneous pipet and read function enables fast kinetic assays such as calcium flux in multiple wells
- Cell suspension system with adjustable stirring speed, pump, and pipetting parameters facilitates optimization with different cell types
- Cell suspension system eliminates the need for separate compound plate during Aequorin assays
- FLIPR TetraCycler Plate Handler enables microplate and pipette tip changes and facilitates integration to laboratory robotics systems
- Software displays only options relevant to the instrument configuration and eliminates the opportunity to make protocol errors
- User-defined protocols can include up to four wash solvents to automate cleaning of cell handling system
- Viewing signal traces, EC50 curves, and Z factors on the fly provides quick data analysis without having to export data to another software program
Assay Kits
- We offer a full line of assay kits optimized for use with the FLIPR Tetra System.
Műszaki specifikációk
General Specifications
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Dimensions (in.)
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39 (W) x 70 (H) x 27 (D)
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Dimensions (cm)
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99 (W) x 178 (H) x 69 (D)
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Weight (approx.)
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850 lbs. (386 kg)
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Power consumption
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600 VA
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Power Source
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90-240 vAC, 50-60 Hz
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Operating system
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Windows XP or Windows 7
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Excitation Optics
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Source
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Light-emitting diodes (LED) or no source
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Wavelength range*
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335-626nm*
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Calcium (default)
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470-495nm
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Membrane potential
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510-545nm
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Voltage sensor probes
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390-420nm
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Fura
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335-345nm
380-390nm |
* For complete details on the wavelengths addressed, please follow this link.
Emission Optics
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Camera Type
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EMCCD
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ICCD
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Detection
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Fluorescence
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Luminescence & Fluorescence
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Mode
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Applikációk
The FLIPR Tetra System supports numerous assay categories including:
Tartozékok, kiszerelések
FLIPR Tetra System utilizes Molecular Devices ScreenWorks® System Control Software to define and run experimental protocols. Using a drag-and-drop interface, protocols can be easily set up to include:
ScreenWorks Software is both flexible and user-friendly. During protocol set-up, only relevant options are displayed, based on the installed fluidics and optics hardware, making it easy to choose parameters that are right for each assay. Live and information-rich data in 96-, 384- or 1536-well plate format is displayed while testing. Specific wells can be grouped for analysis or data export purposes. Graphs and tables can be easily copied and pasted into documents, presentations or worksheets, and different reductions can be selected for group statistics, making results readily accessible.
1 Please contact your local Molecular Devices Sales Representative for details regarding this configure to-order item. FLIPR Tetracycler and Robotic Integration Optional Cell Suspension System and Consumables
An optional cell management system for the FLIPR Tetra System simplifies luminescent calcium mobilization assays and increases throughput by eliminating the need to plate cells and the need for separate compound plates during aequorin assays. Cells are held in spinner flask which maintains a uniform cell suspension and promotes assay robustness. During the assay, cells are pumped to the reservoir for pipetting and returned to the spinner flask. Adjustable stir speed, pump speeds and pipetting parameters simplify the optimization of cell handling for different cell lines. A variety of flask sizes are available to scale the volume for assay development through high throughput screening. Requires Part number 03010-5339 field installation of Cell Suspension system.
Videók, ismertetők
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