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BIO SCIENCE
Promega

Genetic Identity

Promega offers STR systems to amplify the expanded CODIS loci, ENFSI-recommended loci and other loci such as the low-stutter pentanucleotide markers Penta D and Penta E.
Promega DNA extraction systems yield pure, intact DNA and are amenable to automation. Promega also offers reagents to pretreat swabs and storage card punches prior to direct amplification. Learn how these products can process your samples faster and more consistently.
Real-time PCR-based systems allow you to accurately quantify human genomic DNA prior to STR amplification. The PowerQuant™ System also assesses DNA integrity and detects PCR inhibitors.
Automation of time-consuming steps increases sample throughput and allows DNA analysts to spend time on more exacting tasks.

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Automation for Genetic Identity 

Identity Automation™ for Normalization and the PowerPlex® System

The STR Normalization Manager™ has been created to add control and functionality to automated STR amplification setup.

DNA IQ™ System

DNA extraction using the DNA IQ™ System has been automated on a number of platforms, including the Biomek® 3000, Tecan Freedom EVO® and Maxwell® 16 Instruments.

Automated Differex™ System

The Differex™ System is the first and only system that allows a forensic laboratory to automate every step of differential extraction. Process up to 48 differential extractions in less than 5 hours, with less than 1 hour of hands-on time.

Plexor® HY System

Setup of Plexor® HY reactions can be automated, removing user-to-user variability from qPCR and cutting hands-on time from an hour or more to just minutes.

DNA IQ™ Reference and Casework Sample Kits for Maxwell® 16

These kits employ the trusted DNA IQ™ reagents and Maxwell® 16 Instrument to purify DNA from reference and casework samples, including buccal swabs, FTA® blood cards, stains and trace DNA samples.

 

DNA Quantification for Genetic Identity 

PowerQuant™ System

The more information you have about a DNA sample, the better your chance for successful STR analysis. The PowerQuant™ System uses three multicopy targets and an Internal PCR Control to quantify autosomal and male (Y) DNA, assess the level of DNA degradation and detect PCR inhibitors.

Plexor® HY System

This real-time PCR system simultaneously quantifies total human DNA and male DNA using the Plexor® technology, which provides consistent DNA detection down to 6.4pg.

 

Sample Preparation for Genetic Identity

SwabSolution™ and PunchSolution™ Kits and AmpSolution™ Reagent

The SwabSolution™ Kit, PunchSolution™ Kit and AmpSolution™ Reagent are used to process swabs and storage card punches for direct amplification using PowerPlex® Systems.

DNA IQ™ System

The paramagnetic DNA IQ™ Resin removes PCR inhibitors and contaminants frequently encountered in casework samples, allowing you to isolate pure DNA from reference and casework samples.

Casework Extraction Kit (for use with DNA IQ™ Casework Pro Kit and Maxwell® 16 System)

A convenient kit to increase yield of extracted DNA from challenging casework samples and substrates.

DNA IQ™ Reference and Casework Sample Kits for Maxwell® 16
These kits employ the trusted DNA IQ™ reagents and Maxwell® 16 Instrument to purify DNA from reference and casework samples, including buccal swabs, FTA® blood cards, stains and trace DNA samples.
 
Automated Differex™ System

The Differex™ System is the first and only system that allows a forensic laboratory to automate every step of differential extraction. Process up to 48 differential extractions in less than 5 hours, with less than 1 hour of hands-on time.

Manual Differex™ System

The Differex™ System extracts DNA from sexual assault samples easily and quickly. Recently, the manual Differex™ System protocol was improved for better separation of epithelial and sperm fractions.

Slicprep® 96 Device

This device allows simultaneous centrifugation of 96 samples and is designed so that both the proteinase K digestion or cell lysis and centrifugation can be performed in the same device.

STR Analysis for Forensic and Paternity Testing 

PowerPlex® Fusion Systems

Five-color and six-color fluorescent systems that co-amplify the expanded CODIS core loci and European Standard Set loci. These systems offer the highest discrimination from a single reaction and delivers more information for demanding forensic, paternity and relationship testing cases.

PowerPlex® Y23 System

The PowerPlex® Y23 system is a rapid human identification Y-STR assay for forensic casework, offender databasing and relationship testing. The five-color system uses rapid cycling to co-amplify 23 Y-STR loci and direct-amplification protocols for common sample types.

PowerPlex® ESX and ESI Fast Systems

The PowerPlex® ESX and ESI Fast Systems are rapid (≤50-minute cycling time) human-identification STR assays for forensic casework, offender databasing and relationship testing.

PowerPlex® 21 System

A rapid human identification STR system for forensic casework, offender databasing and relationship testing.

PowerPlex® 18D System

The PowerPlex® 18D System allows direct amplification and four-color fluorescent detection of seventeen STR loci and Amelogenin. The reduced amplification time allows easier and faster genotyping for database and paternity laboratories.

www.promega.com

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